MedKoo Cat#: 462302 | Name: VE607

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VE607 is an inhibitor of SARS-CoV virus entry. VE607 can specifically inhibit SARS-CoV virus entry into cells with an EC50 value of 3 μM and inhibited SARS-CoV plaque formation with an IC50 of 1.6 μM.

Chemical Structure

VE607
VE607
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 462302

Name: VE607

CAS#: unknown

Chemical Formula: C22H36N2O4

Exact Mass: 392.2675

Molecular Weight: 392.54

Elemental Analysis: C, 67.32; H, 9.24; N, 7.14; O, 16.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
VE607; VE-607; VE 607
IUPAC/Chemical Name
3,3'-(1,3-phenylenebis(oxy))bis(1-(piperidin-1-yl)propan-2-ol)
InChi Key
FHFSLXLDKXBOQN-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H36N2O4/c25-19(15-23-10-3-1-4-11-23)17-27-21-8-7-9-22(14-21)28-18-20(26)16-24-12-5-2-6-13-24/h7-9,14,19-20,25-26H,1-6,10-13,15-18H2
SMILES Code
OC(COC1=CC=CC(OCC(O)CN2CCCCC2)=C1)CN3CCCCC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 392.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: 1: Inhibitors of SARS-CoV-2 Entry: Current and Future Opportunities. Siyu Xiu, Alexej Dick, Han Ju, Sako Mirzaie, Fatemeh Abdi, Simon Cocklin, Peng Zhan, Xinyong Liu. J Med Chem. 2020 Jun 15 : acs.jmedchem.0c00502. Published online 2020 Jun 15. doi: 10.1021/acs.jmedchem.0c00502. PMCID: PMC7315836