IUPAC/Chemical Name
1-Butanaminium, 3-((4-butoxybenzoyl)oxy)-N,N,N-triethyl-2-methyl-, iodide
InChi Key
QNHKOBBQUXITDC-UHFFFAOYSA-M
InChi Code
InChI=1S/C22H38NO3.HI/c1-7-11-16-25-21-14-12-20(13-15-21)22(24)26-19(6)18(5)17-23(8-2,9-3)10-4;/h12-15,18-19H,7-11,16-17H2,1-6H3;1H/q+1;/p-1
SMILES Code
CC(OC(C1=CC=C(OCCCC)C=C1)=O)C(C)C[N+](CC)(CC)CC.[I-]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
491.45
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Torosian AA. Lechenie gipertonicheskoĭ bolezni kvateronom i preparatami rauvol'fii zmeinoĭ [Treatment of hypertension with quateron and Rauwolfia serpentina compounds]. Vrach Delo. 1968 Feb;2:147-8. Russian. PMID: 4386038.
2: Khutorova LS. Fepromaron. Kvateron [Phepromaron. Quateron]. Feldsher Akush. 1972 Mar;37(3):37-8. Russian. PMID: 4402188.
3: Virabian IL. Ekskretsiia atsetilkholina slizistoĭ obolockhi zheludka i ego kolichestvennye izmeneniia pod vliianiem ganglerona i kvaterona [Excretion of acetylcholine by the gastric mucosa and its quantitative modification under the effect of gangleron and quateron]. Zh Eksp Klin Med. 1967;7(1):13-24. Russian. PMID: 4391198.
4: Mirzoian SA, Virabian TL. Analiz deĭstviia kvaterona na soderzhanie adrenalina i noradrenalina v razlichnykh sloiakh zheludka [Analysis of the effect of quateron on the level of adrenalin and noradrenalin in various stomach strata]. Biull Eksp Biol Med. 1969 Oct;68(10):56-8. Russian. PMID: 4395275.
5: Virabian TL. Mitokhondrial'nye monoaminoksidazy v mozge, zheludke i pecheni pri éksperimental'noĭ iazye zheludka i izmenenie ikh aktivnosti pod vliianiem kvaterona [Mitochondrial monoamine oxidase in the brain, stomach and liver in experimental gastric ulcer and the change in their activity under the influence of quateron]. Zh Eksp Klin Med. 1976;16(5):11-9. Russian. PMID: 1023702.
6: Vakhrushev IaM. Lechenie bol'nykh iazvennoĭ bolezn'iu metiluratsilom v sochetanii s kvateronom [Treatment of peptic ulcer with methyluracil in combination with quateron]. Sov Med. 1973 Jun;36(6):140-1. Russian. PMID: 4147788.
7: Barsegian BA. Vliianie kvaterona na fil'tratsionno-reabsorbtsionnuiu funktsiiu pochek pri gipertonicheskoĭ bolezni [Effect of quateron on the filtration-reabsorption activity of the kidney in hypertension]. Zh Eksp Klin Med. 1965;5(3):47-51. Russian. PMID: 4378990.
8: Broevskaia BD. Lechenie bol'nykh iazvennoĭ bolezn'iu kvateronom i gangleronom [Treatment of the patients with peptic ulcer by quateron and gangleron]. Vrach Delo. 1967 Oct;10:115-6. Russian. PMID: 4390205.
9: DAVIDOVSKII NM. [Data on the clinical use of Quateron, a new ganglion- blocking agent, in the treatment of patients with angina pectoris]. Ter Arkh. 1962 Oct;34:55-8. Russian. PMID: 14025338.
10: Leshchinskiĭ LA, Pevchikh VV, Trusov VV, Vakhrushev IaM, Verevkin AM. Sravnitel'noe issledovanie éffektivnosti nerobola, kvaterona i ikh sochetaniĭ priiazvennoĭ bolezni zheludka i dvenadtsatiperstnoi kishki [Comparative study of the effectiveness of nerobol and quateron, and their combinations in stomach and duodenal ulcers]. Klin Med (Mosk). 1972 Mar;50(3):68-73. Russian. PMID: 4401983.
11: Mirzoian SA, Virabian TL. Vliianie kvaterona na soderzhanie dofamina i DOFA v tkaniakh zheludka pri ego éksperimental'noĭ iazve [Effect of quateron on the dopamine and DOPA content in the stomach tissues in experimental ulcer]. Farmakol Toksikol. 1980 Jan-Feb;43(1):71-4. Russian. PMID: 6103821.
12: el-Sajed MA. Spektrofotometrychne vyznachennia hanhleronu i kvateronu v UF oblasti [Spectrophotometric determination of gangleron and quateron in UV region]. Farm Zh. 1970 Jan-Feb;25(1):33-7. Ukrainian. PMID: 4392876.
13: Virabian TL, Tatevosian TS, Ovsepian SA. Sravnitel'noe morfo-biokhimicheskoe issledovanie izmenenii v stenke zheludka pri ego éksperimental'noĭ iazve v usloviiakh primeneniia kvaterona [Comparative morphobiochemical study of the changes in the stomach wall in experimental ulcer under the use of Quateron]. Zh Eksp Klin Med. 1978;18(3):37-43. Russian. PMID: 685600.
14: Mirzoian SA, Nazaretian RA, Sarkisian AM. Soderzhanie katekholaminov v razlichnykh otdelakh zheludka pri éksperimental'noĭ distrofii i v usloviiakh primeneniia kvaterona [Catecholamine content of different parts of the stomach in experimental dystrophy and under conditions of quateron administration]. Farmakol Toksikol. 1969 May-Jun;32(3):301-4. Russian. PMID: 4390256.
15: Tsimmerman IaS, Valirakhmanova TD. Primenenie kvaterona i sochetaniia prednizolona s nerobolom pri lechenii bol'nykh khronicheskim gastritom s sekretornoĭ nedostatochnost'iu [Use of quateron and a combination of prednisolone with nerobol in treating chronic gastritis with secretory insufficiency]. Vrach Delo. 1975 Feb;(2):55-9. Russian. PMID: 1136408.
16: Mnatsakanov TS, Barsegian BA. Ostrye nabliudeniia nad deĭstviem kvaterona pri gipertonicheskoĭ bolezni [Acute obsdrvations of the action of quateron in hypertension]. Zh Eksp Klin Med. 1967;7(2):31-5. Russian. PMID: 4387711.
17: Vakhrushev IaM. Opyt terapevticheskogo primeneniia anabolicheskogo steroida Nerobola v kombinatsii s Kvateronom pri obostreniiakh iazvennoi bolezni [Therapeutic use of anabolic steroid Nerobol in combination with Quateron in exacerbation of peptic ulcer]. Ter Arkh. 1971 Oct;43(10):26-30. Russian. PMID: 4400959.
18: Trusov VV, Vakhrushev YaM. Opyt klinicheskogo primeneniia khlorida metilmetioninsulfoniia (vitamina U) v kombinatsii s antikhlinergicheskim preparatom kvateronom pri obostreniiakh iazvennoĭ bolezni [Experience in clinical use of chloride methylmethionin sulfonium (vitamin V) in combination with anticholinergic preparation quateron in exacerbation of ulcer disease]. Ter Arkh. 1972 Oct;44(10):37-41. Russian. PMID: 4659384.
19: Shumilo TV. Fotokolorymetrychne vyznachenniâ oksylidynu i kvateronu [Photocolorimetric determination of oxylidin and quateron]. Farm Zh. 1971;26(3):29-31. Ukrainian. PMID: 4399337.
20: Pashinian SA, Martirosian TA, Konobeeva GI. Vliianie kvaterona na sostoianie sokratitel'nogo miokarda pri eksperimental'noĭ ostroĭ serdechnoĭ nedostatochnosti [Effect of quateron on the state of contractile processes in the myocardium in experimental acute cardiac insufficiency]. Zh Eksp Klin Med. 1975;15(6):44-7. Russian. PMID: 4937.
