MedKoo Cat#: 559002 | Name: BHBM

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BHBM is an acylhydrazone with antifungal activity.

Chemical Structure

BHBM
BHBM
CAS#302807-84-7

Theoretical Analysis

MedKoo Cat#: 559002

Name: BHBM

CAS#: 302807-84-7

Chemical Formula: C15H13BrN2O2

Exact Mass: 332.0160

Molecular Weight: 333.19

Elemental Analysis: C, 54.07; H, 3.93; Br, 23.98; N, 8.41; O, 9.60

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Synonym
BHBM
IUPAC/Chemical Name
2-methyl-benzoic acid 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
InChi Key
ZREZUYGIIHJUAR-RQZCQDPDSA-N
InChi Code
InChI=1S/C15H13BrN2O2/c1-10-4-2-3-5-13(10)15(20)18-17-9-11-8-12(16)6-7-14(11)19/h2-9,19H,1H3,(H,18,20)/b17-9+
SMILES Code
O=C(N/N=C/C1=CC(Br)=CC=C1O)C2=CC=CC=C2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 333.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Haranahalli, K., Lazzarini, C., Sun, Y., et al. SAR studies on aromatic acylhydrazone-based inhibitors of fungal sphingolipid synthesis as next-generation antifungal agents. J. Med. Chem. 62(17), 8249-8273 (2019). 2. Lazzarini, C., Haranahalli, K., Rieger, R., et al. Acylhydrazones as antifungal agents targeting the synthesis of fungal sphingolipids. Antimicrob. Agents Chemother. 62(5), e00156-00118 (2018).