MedKoo Cat#: 559000 | Name: Vobtusine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Vobtusine is an alkaloid that has been found in V. africana leaves and has been found to show in-vitro cytotoxicity and possess anti-proliferative properties.

Chemical Structure

Vobtusine
Vobtusine
CAS#19772-79-3

Theoretical Analysis

MedKoo Cat#: 559000

Name: Vobtusine

CAS#: 19772-79-3

Chemical Formula: C43H50N4O6

Exact Mass: 718.3730

Molecular Weight: 718.89

Elemental Analysis: C, 71.84; H, 7.01; N, 7.79; O, 13.35

Price and Availability

Size Price Availability Quantity
1mg USD 600.00 2 Weeks
5mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
NSC 180540, NSC180540, NSC-180540, Vobtusin
IUPAC/Chemical Name
(2S,2aS,3′aR,4′aR,5aR,12bR,12′bR,12′cR,15aR,15′aS,17′aS)-2′,3′,4,4′a,5,6,8,12′c,13,13′,14,14′,17′,17′a-tetradecahydro-12′c-hydroxy-9′-methoxy-spiro[1H,15aH-furo[2′,3′:7,8]indolizino[8,1-cd]carbazole-2(2aH),6′(7′H)-[4H,5H,15aH,16H]furo[2′,3′:7,8]indolizino[8,1-cd]pyrido[1,2,3-lm]carbazole]-7-carboxylic acid, methyl ester
InChi Key
IIMPGJMHQMBXKL-OPDPKHDKSA-N
InChi Code
InChI=1S/C43H50N4O6/c1-50-30-9-5-7-28-32(30)47-24-38(20-25-21-39-13-18-52-31(39)10-15-45-17-12-42(28,36(39)45)43(25,47)49)23-46-16-11-41-27-6-3-4-8-29(27)44-33(41)26(34(48)51-2)22-40(35(41)46)14-19-53-37(38)40/h3-9,25,31,35-37,44,49H,10-24H2,1-2H3/t25-,31+,35+,36+,37+,38+,39-,40+,41+,42-,43-/m1/s1
SMILES Code
COC1=C(N2[C@]3(O)[C@@]45[C@](N6CC5)([H])[C@]([C@]7([H])CC6)(CCO7)C[C@@]3([H])C[C@]8(CN(CC9)[C@@]([C@@]9(C%10=CC=CC=C%10N%11)C%11=C(C(OC)=O)C%12)([H])[C@]%13%12[C@@]8([H])OCC%13)C2)C4=CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 718.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Koroch, A.R., Juliani, H.R., Kulakowski, D., et al. Voacanga africana: Chemistry, quality and pharmacological activity. African Natural Plant Products: New Discoveries and Challenges in Chemistry and Quality 1021, 363-380 (2009).