Apcin-A is an anaphase-promoting complex (APC) inhibitor. Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V.
MedKoo Cat#: 462255
Name: Apcin-A
CAS#: 1683617-62-0
Chemical Formula: C10H14Cl3N5O2
Exact Mass: 341.0213
Molecular Weight: 342.61
Elemental Analysis: C, 35.06; H, 4.12; Cl, 31.04; N, 20.44; O, 9.34
The following data is based on the product molecular weight 342.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
