TP3011 is an active metabolite of CH-0793076 and is a potent topoisomerase I inhibitor equipotent as SN38. TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro.
MedKoo Cat#: 462253
Name: TP3011
CAS#: 534605-74-8
Chemical Formula: C26H26N4O5
Exact Mass: 474.1903
Molecular Weight: 474.52
Elemental Analysis: C, 65.81; H, 5.52; N, 11.81; O, 16.86
The following data is based on the product molecular weight 474.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
