MedKoo Cat#: 462249 | Name: EZH2-IN-2
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

EZH2-​IN-​2 is a EZH2 inhibitor. It can be used for the research of cancer or precancerous condition related to EZH2 activity.

Chemical Structure

EZH2-IN-2
EZH2-IN-2
CAS#2238821-31-1

Theoretical Analysis

MedKoo Cat#: 462249

Name: EZH2-IN-2

CAS#: 2238821-31-1

Chemical Formula: C35H44N6O3

Exact Mass: 596.3475

Molecular Weight: 596.78

Elemental Analysis: C, 70.44; H, 7.43; N, 14.08; O, 8.04

Price and Availability

Size Price Availability Quantity
10mg USD 700.00 2 Weeks
50mg USD 1,650.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
EZH2-IN-2; EZH2 inhibitor 2
IUPAC/Chemical Name
3-(6-(4-(cyclopropylmethyl)piperazin-1-yl)-2-methylpyridin-3-yl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(N-ethylcyclopropanecarboxamido)benzamide
InChi Key
PGKJDHCNKZYHCR-UHFFFAOYSA-N
InChi Code
InChI=1S/C35H44N6O3/c1-5-41(35(44)26-8-9-26)29-18-27(17-28(19-29)33(42)36-20-31-22(2)16-23(3)37-34(31)43)30-10-11-32(38-24(30)4)40-14-12-39(13-15-40)21-25-6-7-25/h10-11,16-19,25-26H,5-9,12-15,20-21H2,1-4H3,(H,36,42)(H,37,43)
SMILES Code
CC1=NC(N2CCN(CC3CC3)CC2)=CC=C1C4=CC(N(CC)C(C5CC5)=O)=CC(C(NCC6=C(C)C=C(C)NC6=O)=O)=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 596.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: LIU, Qing Song, et al. Ezh2 inhibitor and use thereof. WO2018133795A1.