XP-59 is a potent inhibitor of the SARS-CoV main protease (Mpro), exhibiting a Ki of 0.1 μM and disrupting viral replication. Its benzotriazole ester core is essential for binding affinity, making it a promising lead for antiviral drug development. In preclinical studies, XP-59 significantly reduces viral load in infected cell cultures.
MedKoo Cat#: 462223
Name: XP-59
CAS#: 890402-73-0
Chemical Formula: C15H14N4O2
Exact Mass: 282.1117
Molecular Weight: 282.30
Elemental Analysis: C, 63.82; H, 5.00; N, 19.85; O, 11.33
The following data is based on the product molecular weight 282.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
