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MedKoo Cat#: 462213 | Name: PSB 0474

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PSB 0474 is a potent and selective P2Y6 agonist.

Chemical Structure

PSB 0474
PSB 0474
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 462213

Name: PSB 0474

CAS#: unknown

Chemical Formula: C17H18N2Na2O13P2

Exact Mass: 566.0080

Molecular Weight: 566.26

Elemental Analysis: C, 36.06; H, 3.20; N, 4.95; Na, 8.12; O, 36.73; P, 10.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
PSB 0474
IUPAC/Chemical Name
3-(2-Oxo-2-phenylethyl)-uridine-5'-diphosphate disodium salt
InChi Key
LEICCBKKYICWFH-BWBFMJMBSA-L
InChi Code
InChI=1S/C17H20N2O13P2.2Na/c20-11(10-4-2-1-3-5-10)8-19-13(21)6-7-18(17(19)24)16-15(23)14(22)12(31-16)9-30-34(28,29)32-33(25,26)27;;/h1-7,12,14-16,22-23H,8-9H2,(H,28,29)(H2,25,26,27);;/q;2*+1/p-2/t12-,14-,15-,16-;;/m1../s1
SMILES Code
O[C@@H]([C@H]([C@H](N1C(N(CC(C2=CC=CC=C2)=O)C(C=C1)=O)=O)O3)O)[C@H]3COP([O-])(OP([O-])(O)=O)=O.[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 566.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: El-Tayeb A, Qi A, Müller CE. Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptors. J Med Chem. 2006;49(24):7076-7087. doi:10.1021/jm060848j 2: Mitchell C, Syed NI, Tengah A, Gurney AM, Kennedy C. Identification of contractile P2Y1, P2Y6, and P2Y12 receptors in rat intrapulmonary artery using selective ligands. J Pharmacol Exp Ther. 2012;343(3):755-762. doi:10.1124/jpet.112.198051