MedKoo Cat#: 574437 | Name: VUF-5681 dihydrobromide
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUF-5681 dihydrobromide is a selective and potent agonist of the GPR17 receptor, a G-protein-coupled receptor involved in neuroinflammation and remyelination processes. It has been studied for its potential role in modulating oligodendrocyte precursor cell differentiation, making it relevant for research in multiple sclerosis and other demyelinating diseases.

Chemical Structure

VUF-5681 dihydrobromide
VUF-5681 dihydrobromide
CAS#639089-06-8

Theoretical Analysis

MedKoo Cat#: 574437

Name: VUF-5681 dihydrobromide

CAS#: 639089-06-8

Chemical Formula: C11H21Br2N3

Exact Mass: 353.0102

Molecular Weight: 355.12

Elemental Analysis: C, 37.20; H, 5.96; Br, 45.00; N, 11.83

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
50mg USD 1,000.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
VUF-5681 dihydrobromide, VUF-5681 2HBr
IUPAC/Chemical Name
4-[3-(1H-Imidazol-4-yl)propyl]piperidine dihydrobromide
InChi Key
YFFVIGXPKWSZHW-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H19N3.2BrH/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10;;/h8-10,12H,1-7H2,(H,13,14);2*1H
SMILES Code
[H]Br.[H]Br.C1(CCCC2=CNC=N2)CCNCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 355.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Kitbunnadaj et al (2004) Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H3 receptor agonist. J.Med.Chem. 47 2414 PMID: 15115383 2. Leurs et al (2005) The histamine H3 receptor: from gene cloning to H3 receptor drugs. Nat.Rev.Drug Discov. 4 107 PMID: 15665857 3. Moreno-Delgado et al (2006) Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway. Neuropharmacology 51 517 PMID: 16769092