MedKoo Cat#: 574431 | Name: TC-MCH 7c
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TC-MCH 7c is a selective melanin-concentrating hormone receptor 1 (MCH1R) antagonist that has been shown to decrease body weight in a mouse model of diet-induced obesity.

Chemical Structure

TC-MCH 7c
TC-MCH 7c
CAS#864756-35-4

Theoretical Analysis

MedKoo Cat#: 574431

Name: TC-MCH 7c

CAS#: 864756-35-4

Chemical Formula: C24H25FN2O3

Exact Mass: 408.1849

Molecular Weight: 408.47

Elemental Analysis: C, 70.57; H, 6.17; F, 4.65; N, 6.86; O, 11.75

Price and Availability

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10mg USD 465.00 2 Weeks
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Related CAS #
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Synonym
TC-MCH 7c
IUPAC/Chemical Name
4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone
InChi Key
ANCFKYJMXNMYNZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H25FN2O3/c25-20-5-3-19(4-6-20)18-30-23-11-14-27(24(28)17-23)21-7-9-22(10-8-21)29-16-15-26-12-1-2-13-26/h3-11,14,17H,1-2,12-13,15-16,18H2
SMILES Code
O=C1C=C(OCC2=CC=C(F)C=C2)C=CN1C3=CC=C(OCCN4CCCC4)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 408.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Haga et al (2011) Discovery of novel phenylpyridone derivatives as potent and selective MCH1R antagonists. Bioorg.Med.Chem. 19 883 PMID: 21190859 2. Ito et al (2009) Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice. Eur.J.Pharmacol. 624 77 PMID: 19836369