MedKoo Cat#: 574398 | Name: SB-268262

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SB-268262 is a selective non-peptide CGRP1 antagonist that inhibits [125I]CGRP binding and CGRP-activated adenylyl cyclase stimulation in SK-N-MC cell membranes.

Chemical Structure

SB-268262
SB-268262
CAS#217438-17-0

Theoretical Analysis

MedKoo Cat#: 574398

Name: SB-268262

CAS#: 217438-17-0

Chemical Formula: C18H15N3O4S2

Exact Mass: 401.0504

Molecular Weight: 401.45

Elemental Analysis: C, 53.85; H, 3.77; N, 10.47; O, 15.94; S, 15.97

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
No Data
Synonym
SB-268262, SB268262, SB 268262
IUPAC/Chemical Name
N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide
InChi Key
YXHLPJQQPOMPGE-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3
SMILES Code
O=C(N(C)C1=CC=CC=C1C)C2=CC=C(S(C3=NC=CS3)=O)C([N+]([O-])=O)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Aiyar et al (2001) Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist. J.Pharmacol.Exp.Ther. 296 768 PMID: 11181905