MedKoo Cat#: 574363 | Name: GSK-789472 hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK-789472 hydrochloride is a selective dopamine D3 receptor antagonist and D2 partial agonist.

Chemical Structure

GSK-789472 hydrochloride
GSK-789472 hydrochloride
CAS# 1257326-24-1

Theoretical Analysis

MedKoo Cat#: 574363

Name: GSK-789472 hydrochloride

CAS#: 1257326-24-1

Chemical Formula: C15H22ClN3O

Exact Mass: 0.0000

Molecular Weight: 295.81

Elemental Analysis: C, 60.91; H, 7.50; Cl, 11.98; N, 14.21; O, 5.41

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
250mg USD 850.00 2 Weeks
1g USD 1,450.00 2 Weeks
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Related CAS #
No Data
Synonym
GSK-789472 hydrochloride; GSK-789472 HCl; GSK789472 HCl; GSK 789472 HCl; Dopamine D2 receptor agonist-3
IUPAC/Chemical Name
1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one;hydrochloride
InChi Key
BYJUVPWUMBVSTK-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H21N3O.ClH/c19-15-17(12-13-6-4-5-9-16-13)10-11-18(15)14-7-2-1-3-8-14;/h1-3,7-8,13,16H,4-6,9-12H2;1H
SMILES Code
O=C1N(C2=CC=CC=C2)CCN1CC3NCCCC3.Cl
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
GSK-789472 hydrochloride is a selective dopamine D3 receptor antagonist and D2 partial agonist.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 295.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1. Holmes et al (2010) The identification of a selective DA D2 partial agonist, D3 antagonist displaying high levels of brain exposure. Bioorg.Med.Chem.Lett. 20 2013 PMID: 20153647