MedKoo Cat#: 574359 | Name: FPR A14
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

FPR A14 is a formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro. It may induce dose-dependent differentiation of mouse neuroblastoma N2a cells.

Chemical Structure

FPR A14
FPR A14
CAS#329691-12-5

Theoretical Analysis

MedKoo Cat#: 574359

Name: FPR A14

CAS#: 329691-12-5

Chemical Formula: C23H20N2O5

Exact Mass: 404.1372

Molecular Weight: 404.42

Elemental Analysis: C, 68.31; H, 4.98; N, 6.93; O, 19.78

Price and Availability

Size Price Availability Quantity
10mg USD 365.00 2 Weeks
25mg USD 750.00 2 Weeks
50mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
FPR A14; FPRA14; FPR-A14;
IUPAC/Chemical Name
1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide
InChi Key
ULOKADSYVZOTTL-ZMOGYAJESA-N
InChi Code
InChI=1S/C23H20N2O5/c1-27-21-11-17(7-9-19(21)28-14-16-5-3-2-4-6-16)13-24-25-23(26)18-8-10-20-22(12-18)30-15-29-20/h2-13H,14-15H2,1H3,(H,25,26)/b24-13+
SMILES Code
O=C(C1=CC=C(OCO2)C2=C1)N/N=C/C3=CC=C(OCC4=CC=CC=C4)C(OC)=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 404.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Schepetkin et al (2007) High-throughput screening for small molecule activators of neutrophils: Identification of novel N-formyl peptide receptor agonists. Mol.Pharmacol. 71 1061 PMID: 17229869 2. Cussell et al (2019) The formyl peptide receptor agonist FPRa14 induces differentiation of Neuro2a mouse neuroblastoma cells into multiple distinct morphologies which can be specifically inhibited with FPR antagonists and FPR knockdown using siRNA. PLoS One 14 e0217815 PMID: 31170199