MedKoo Cat#: 574334 | Name: LUN 02946
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

LUN 02946, also known as Arecaidine propargyl ester tosylate is a potent muscarinic receptor agonist with selectivity for cardiac versus ileal M2 receptors. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

LUN 02946
LUN 02946
CAS# 147202-94-6

Theoretical Analysis

MedKoo Cat#: 574334

Name: LUN 02946

CAS#: 147202-94-6

Chemical Formula: C17H21NO5S

Exact Mass: 351.1140

Molecular Weight: 351.42

Elemental Analysis: C, 58.10; H, 6.02; N, 3.99; O, 22.76; S, 9.12

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 1,050.00 2 Weeks
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Synonym
Arecaidine propargyl ester tosylate; LUN02946; LUN-02946; LUN 02946
IUPAC/Chemical Name
N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate
InChi Key
LYHWIOMAWPVTPI-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H13NO2.C7H8O3S/c1-3-7-13-10(12)9-5-4-6-11(2)8-9;1-6-2-4-7(5-3-6)11(8,9)10/h1,5H,4,6-8H2,2H3;2-5H,1H3,(H,8,9,10)
SMILES Code
CC1=CC=C(C=C1)S(O)(=O)=O.CN1CCC=C(C1)C(=O)OCC#C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 351.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Barlow and Weston-Smith (1985) The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi. Br.J.Pharmacol. 85 437 PMID: 3896364 Moser et al (1989) Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes. Br.J.Pharmacol. 96 319 PMID: 2924082