(Z)-4EGI-1 is the Z-isomer of 4EGI-1 and is an inhibitor of eIF4E/eIF4G interaction and of translation initiation. (Z)-4EGI-1 effectively binds to eIF4E and has anti-cancer activity.
MedKoo Cat#: 462180
Name: (Z)-4EGI-1
CAS#: 901787-88-0
Chemical Formula: C18H12Cl2N4O4S
Exact Mass: 449.9956
Molecular Weight: 451.28
Elemental Analysis: C, 47.91; H, 2.68; Cl, 15.71; N, 12.42; O, 14.18; S, 7.10
The following data is based on the product molecular weight 451.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
