MedKoo Cat#: 574317 | Name: C-171 STING inhibitor
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

C-171 STING inhibitor is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.

Chemical Structure

C-171 STING inhibitor
C-171 STING inhibitor
CAS#2244881-69-2

Theoretical Analysis

MedKoo Cat#: 574317

Name: C-171 STING inhibitor

CAS#: 2244881-69-2

Chemical Formula: C17H20N2O4

Exact Mass: 316.1423

Molecular Weight: 316.36

Elemental Analysis: C, 64.54; H, 6.37; N, 8.86; O, 20.23

Price and Availability

Size Price Availability Quantity
10mg USD 250.00 2 Weeks
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
C-171, C-171 STING inhibitor
IUPAC/Chemical Name
N-(4-hexylphenyl)-5-nitro-2-furancarboxamide
InChi Key
WZVGWJZGQFSRBG-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H20N2O4/c1-2-3-4-5-6-13-7-9-14(10-8-13)18-17(20)15-11-12-16(23-15)19(21)22/h7-12H,2-6H2,1H3,(H,18,20)
SMILES Code
O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCCCC)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 316.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Haag, S.M., Gulen, M.F., Reymond, L., et al. Targeting STING with covalent small-molecule inhibitors. Nature 559(7713), 269-273 (2018). 2. Zhang, H., You, Q.-D., and Xu, X.-L. Targeting stimulator of interferon genes (STING): A medicinal chemistry perspective. J. Med. Chem. 63(8), 3785-3816 (2019).