MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 534790 | Name: MS 28

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS 28 reverses both the respiratory depressant & antinociceptive effects of morphine.

Chemical Structure

MS 28
MS 28
CAS#117523-45-2

Theoretical Analysis

MedKoo Cat#: 534790

Name: MS 28

CAS#: 117523-45-2

Chemical Formula: C24H27N3O2

Exact Mass: 389.2103

Molecular Weight: 389.50

Elemental Analysis: C, 74.01; H, 6.99; N, 10.79; O, 8.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
MS 28; MS-28; MS28
IUPAC/Chemical Name
2-Furancarboxamide, N-(4-methyl-2-pyridinyl)-N-(1-(2-phenylethyl)-4-piperidinyl)-
InChi Key
NQCPDEKEHVGSIN-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H27N3O2/c1-19-9-13-25-23(18-19)27(24(28)22-8-5-17-29-22)21-11-15-26(16-12-21)14-10-20-6-3-2-4-7-20/h2-9,13,17-18,21H,10-12,14-16H2,1H3
SMILES Code
O=C(C1=CC=CO1)N(C2=NC=CC(C)=C2)C3CCN(CCC4=CC=CC=C4)CC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 389.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Msoka TF, Van Guilder GP, Smulders YM, van Furth M, Bartlett JA, van Agtmael MA. Association of HIV-infection, antiretroviral treatment and metabolic syndrome with large artery stiffness: a cross-sectional study. BMC Infect Dis. 2018 Dec 29;18(1):708. doi: 10.1186/s12879-018-3637-0. Erratum in: BMC Infect Dis. 2019 Feb 22;19(1):187. PMID: 30594160; PMCID: PMC6311066. 2: Deus LA, Sousa CV, Rosa TS, Filho JMS, Santos PA, Barbosa LD, Silva Aguiar S, Souza LHR, Simões HG. Heart rate variability in middle-aged sprint and endurance athletes. Physiol Behav. 2019 Jun 1;205:39-43. doi: 10.1016/j.physbeh.2018.10.018. Epub 2018 Oct 30. PMID: 30389479. 3: Kawamoto N, Fujita T, Fukushima S, Shimahara Y, Kume Y, Matsumoto Y, Yamashita K, Asakura K, Kobayashi J. Functional mitral stenosis after mitral valve repair for Type II dysfunction: determinants and impacts on long-term outcome. Eur J Cardiothorac Surg. 2018 Sep 1;54(3):453-459. doi: 10.1093/ejcts/ezy062. PMID: 29490023. 4: Abulaban A, Altowairqi A, Altowairqi H, Almutairi A, Altalhi S, Alotaibi F, Alabbadi I. Multiple Sclerosis Patients Knowledge in Saudi Arabia. Neurosciences (Riyadh). 2019 Oct;24(4):327-330. doi: 10.17712/nsj.2019.4.20190031. PMID: 31872816. 5: Peebles AT, Bruetsch AP, Lynch SG, Huisinga JM. Dynamic balance in persons with multiple sclerosis who have a falls history is altered compared to non- fallers and to healthy controls. J Biomech. 2017 Oct 3;63:158-163. doi: 10.1016/j.jbiomech.2017.08.023. Epub 2017 Sep 1. PMID: 28889946. 6: Wu X, Jhanji V, Chen H, Lin H, Zhang G, Brelen M, Chen W. Change in flash visual evoked potentials in New Zealand albino rabbits after sub-tenon's anesthesia. Cutan Ocul Toxicol. 2017 Jun;36(2):118-124. doi: 10.1080/15569527.2016.1189929. Epub 2016 Dec 13. PMID: 27838929. 7: Rusu LD, Cosma GG, Cernaianu SM, Marin MN, Rusu PF, Ciocănescu DP, Neferu FN. Tensiomyography method used for neuromuscular assessment of muscle training. J Neuroeng Rehabil. 2013 Jul 3;10:67. doi: 10.1186/1743-0003-10-67. PMID: 23822158; PMCID: PMC3713716. 8: Uyarel H, Uslu N, Okmen E, Tartan Z, Kasikcioglu H, Dayi SU, Cam N. QT dispersion in sarcoidosis. Chest. 2005 Oct;128(4):2619-25. doi: 10.1378/chest.128.4.2619. PMID: 16236934. 9: Ceccarelli A, Rocca MA, Pagani E, Colombo B, Martinelli V, Comi G, Filippi M. A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes. Neuroimage. 2008 Aug 1;42(1):315-22. doi: 10.1016/j.neuroimage.2008.04.173. Epub 2008 Apr 20. PMID: 18501636. 10: Nam BD, Kim SM, Jung HN, Kim Y, Choe YH. Comparison of quantitative imaging parameters using cardiovascular magnetic resonance between cardiac amyloidosis and hypertrophic cardiomyopathy: inversion time scout versus T1 mapping. Int J Cardiovasc Imaging. 2018 Nov;34(11):1769-1777. doi: 10.1007/s10554-018-1385-2. Epub 2018 May 30. PMID: 29846837. 11: Comabella M, Pradillo JM, Fernández M, Río J, Lizasoain I, Julià E, Moro MA, Sastre-Garriga J, Montalban X. Plasma levels of 15d-PGJ are not altered in multiple sclerosis. Eur J Neurol. 2009 Nov;16(11):1197-201. doi: 10.1111/j.1468-1331.2009.02696.x. Epub 2009 Jun 15. PMID: 19538219. 12: Bunting E, Lambrakos L, Kemper P, Whang W, Garan H, Konofagou E. Imaging the Propagation of the Electromechanical Wave in Heart Failure Patients with Cardiac Resynchronization Therapy. Pacing Clin Electrophysiol. 2017 Jan;40(1):35-45. doi: 10.1111/pace.12964. Epub 2016 Dec 2. PMID: 27790723; PMCID: PMC5266632. 13: O'Connell K, Langdon D, Tubridy N, Hutchinson M, McGuigan C. A preliminary validation of the brief international cognitive assessment for multiple sclerosis (BICAMS) tool in an Irish population with multiple sclerosis (MS). Mult Scler Relat Disord. 2015 Nov;4(6):521-5. doi: 10.1016/j.msard.2015.07.012. Epub 2015 Aug 7. PMID: 26590658. 14: Romão W, Sabino BD, Bueno MI, Vaz BG, Júnior AC, Maldaner AO, de Castro EV, Lordeiro RA, Nascentes CC, Eberlin MN, Augusti R. LSD and 9,10-dihydro-LSD analyses in street drug blotter samples via easy ambient sonic-spray ionization mass spectrometry (EASI-MS). J Forensic Sci. 2012 Sep;57(5):1307-12. doi: 10.1111/j.1556-4029.2012.02237.x. Epub 2012 Aug 6. PMID: 22880936. 15: Bi CF, Qian HR, Peng LJ, Mao LL, Huang X, Xia DY, Lei X, Qi XK. [The correlation factor analysis for conversion of clinically isolated syndrome to multiple sclerosis and neuromyelitis optica]. Zhonghua Nei Ke Za Zhi. 2016 Jun;55(6):460-5. Chinese. doi: 10.3760/cma.j.issn.0578-1426.2016.06.012. PMID: 27256609. 16: Roberto E, Braga AA, Papachristos AV. Closer to Guns: the Role of Street Gangs in Facilitating Access to Illegal Firearms. J Urban Health. 2018 Jun;95(3):372-382. doi: 10.1007/s11524-018-0259-1. PMID: 29744717; PMCID: PMC5993706. 17: Ryder RA, Kitano K, Phipps AM, Enyart MR, Koceja DM. Contralateral conditioning to the soleus H-reflex as a function of age and physical activity. Exp Brain Res. 2016 Jan;234(1):13-23. doi: 10.1007/s00221-015-4430-6. Epub 2015 Sep 10. PMID: 26358124. 18: Fritz NE, Newsome SD, Eloyan A, Marasigan RE, Calabresi PA, Zackowski KM. Longitudinal relationships among posturography and gait measures in multiple sclerosis. Neurology. 2015 May 19;84(20):2048-56. doi: 10.1212/WNL.0000000000001580. Epub 2015 Apr 15. PMID: 25878185; PMCID: PMC4442106. 19: Hughes JR, Stone JL, Fino JJ, Hart LA. Usefulness of different stimuli in visual evoked potentials. Neurology. 1987 Apr;37(4):656-62. doi: 10.1212/wnl.37.4.656. PMID: 3561778. 20: Villar LM, Masjuan J, González-Porqué P, Plaza J, Sádaba MC, Roldán E, Bootello A, Alvarez-Cermeño JC. Intrathecal IgM synthesis in neurologic diseases: relationship with disability in MS. Neurology. 2002 Mar 12;58(5):824-6. doi: 10.1212/wnl.58.5.824. PMID: 11889253.