Synonym
Mrz 2549; Mrz-2549; Mrz2549
IUPAC/Chemical Name
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-(2-methoxypropyl)-6,11-dimethyl-
InChi Key
OYOSCGNGSBDVQJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H27NO2/c1-12(21-4)11-19-8-7-18(3)13(2)17(19)9-14-5-6-15(20)10-16(14)18/h5-6,10,12-13,17,20H,7-9,11H2,1-4H3
SMILES Code
OC1=CC=C2C(C3(C)CCN(CC(OC)C)C(C3C)C2)=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
0.00
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Bowers CY, Sartor AO, Reynolds GA, Badger TM. On the actions of the growth hormone-releasing hexapeptide, GHRP. Endocrinology. 1991 Apr;128(4):2027-35. doi: 10.1210/endo-128-4-2027. PMID: 2004615.
2: Hassen AH, Feuerstein G, Faden AI. Kappa opioid receptors modulate cardiorespiratory function in hindbrain nuclei of rat. J Neurosci. 1984 Sep;4(9):2213-21. doi: 10.1523/JNEUROSCI.04-09-02213.1984. PMID: 6148384; PMCID: PMC6564800.
3: Huffman RD, Frey JM. Response of rat globus pallidus neurons to microintophoretically applied mu and kappa opioid receptor agonists. Eur J Pharmacol. 1989 Nov 7;170(3):179-91. doi: 10.1016/0014-2999(89)90538-4. PMID: 2575994.
4: Pfeiffer DG, Pfeiffer A, Almeida OF, Herz A. Opiate suppression of LH secretion involves central receptors different from those mediating opiate effects on prolactin secretion. J Endocrinol. 1987 Sep;114(3):469-76. doi: 10.1677/joe.0.1140469. PMID: 2822829.
5: Wüster M, Rubini P, Schulz R. The preference of putative pro-enkephalins for different types of opiate receptors. Life Sci. 1981 Sep 21;29(12):1219-27. doi: 10.1016/0024-3205(81)90226-5. PMID: 6117777.
6: Hassen AH, Feuerstein G, Faden AI. Differential cardiovascular effects mediated by mu and kappa opiate receptors in hindbrain nuclei. Peptides. 1983 Sep-Oct;4(5):621-5. doi: 10.1016/0196-9781(83)90007-4. PMID: 6318199.
7: Sartor O, Bowers CY, Reynolds GA, Momany FA. Variables determining the growth hormone response of His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 in the rat. Endocrinology. 1985 Oct;117(4):1441-7. doi: 10.1210/endo-117-4-1441. PMID: 4029086.
8: Pfeiffer A, Herz A, Loriaux DL, Pfeiffer DG. Central kappa- and mu-opiate receptors mediate ACTH-release in rats. Endocrinology. 1985 Jun;116(6):2688-90. doi: 10.1210/endo-116-6-2688. PMID: 2986960.
9: Ensinger HA, Doevendans JE. Plasma levels of opioid analgesics determined by radioreceptor assay. Arzneimittelforschung. 1984;34(5):609-13. PMID: 6540579.
10: Heath RG, Fitzjarrell AT, Walker CF. Kappa opiate receptor agonists: effects on behavior and on brain function and structure in rhesus monkeys. Biol Psychiatry. 1984 Jul;19(7):1045-74. PMID: 6089918.
