MedKoo Cat#: 462136 | Name: (±)-4-CMTB
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(±)-4-CMTB is a positive allosteric modulator of free fatty acid receptor 2 (FFAR2/GPR43). It selectively induces ERK1/2 phosphorylation in 293 T-REx cells expressing human FFAR2, but not FFAR1 or FFAR3.

Chemical Structure

(±)-4-CMTB
(±)-4-CMTB
CAS#300851-67-6

Theoretical Analysis

MedKoo Cat#: 462136

Name: (±)-4-CMTB

CAS#: 300851-67-6

Chemical Formula: C14H15ClN2OS

Exact Mass: 294.0594

Molecular Weight: 294.80

Elemental Analysis: C, 57.04; H, 5.13; Cl, 12.03; N, 9.50; O, 5.43; S, 10.88

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 600.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
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Synonym
(±)-4-CMTB; 4-CMTB; 4-chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide
IUPAC/Chemical Name
2-(4-chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide
InChi Key
AZYDQCGCBQYFSE-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)
SMILES Code
O=C(NC1=NC=CS1)C(C(C)C)C2=CC=C(Cl)C=C2
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Smith, N.J., Ward, R.J., Stoddart, L.A., et al. Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator. Mol. Pharmacol. 80(1), 163-173 (2011).