Brl 20330 | CAS#105369-94-6 | oral prodrug of temocillin

MedKoo Cat#: 462079 | Name: Brl 20330

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Brl 20330 is an oral prodrug of temocillin.

Chemical Structure

Brl 20330

CAS#105369-94-6

Theoretical Analysis

MedKoo Cat#: 462079

Name: Brl 20330

CAS#: 105369-94-6

Chemical Formula: C23H23N2NaO7S2

Exact Mass: 526.0844

Molecular Weight: 526.55

Elemental Analysis: C, 52.46; H, 4.40; N, 5.32; Na, 4.37; O, 21.27; S, 12.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Brl 20330

IUPAC/Chemical Name

sodium (R,Z)-N-((2S,5R,6S)-2-carboxy-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl)-3-oxo-2-(thiophen-3-yl)-3-(o-tolyloxy)propanimidate

InChi Key

DUAKSXABRNOXNK-NIFPISSNSA-M

InChi Code

InChI=1S/C23H24N2O7S2.Na/c1-12-7-5-6-8-14(12)32-19(29)15(13-9-10-33-11-13)17(26)24-23(31-4)20(30)25-16(18(27)28)22(2,3)34-21(23)25;/h5-11,15-16,21H,1-4H3,(H,24,26)(H,27,28);/q;+1/p-1/t15-,16+,21-,23+;/m1./s1

SMILES Code

CC1=CC=CC=C1OC([C@](/C([O-])=N/[C@]([C@](S2)([H])N3[C@@](C2(C)C)([H])C(O)=O)(OC)C3=O)([H])C4=CSC=C4)=O.[Na+]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 526.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Basker MJ, Merrikin DJ, Ponsford RJ, Slocombe B, Tasker TC. BRL 20330, an oral prodrug of temocillin: bioavailability studies in man. J Antimicrob Chemother. 1986;18(3):399‐405. doi:10.1093/jac/18.3.399