MedKoo Cat#: 462054 | Name: Tei 1338

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tei 1338 is a selective lipoxygenase inhibitor. TEI-1338 inhibits infection-stimulated lipoxygenase activity in a concentration-dependent manner, without affecting cyclooxygenase activity.

Chemical Structure

Tei 1338
Tei 1338
CAS#119261-58-4

Theoretical Analysis

MedKoo Cat#: 462054

Name: Tei 1338

CAS#: 119261-58-4

Chemical Formula: C27H27NO3

Exact Mass: 413.1991

Molecular Weight: 413.52

Elemental Analysis: C, 78.42; H, 6.58; N, 3.39; O, 11.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Tei 1338: Tei-1338
IUPAC/Chemical Name
8-(2-Naphthyl)-N-(2-methoxycarbonylphenyl)-5,6-methano-7-octenamide
InChi Key
FHWPXRMQJIZPDX-WWAXUJMESA-N
InChi Code
InChI=1S/C27H27NO3/c1-31-27(30)24-10-4-5-11-25(24)28-26(29)12-6-9-22-18-23(22)16-14-19-13-15-20-7-2-3-8-21(20)17-19/h2-5,7-8,10-11,13-17,22-23H,6,9,12,18H2,1H3,(H,28,29)/b16-14+/t22-,23-/m1/s1
SMILES Code
COC(=O)c1ccccc1NC(=O)CCC[C@@H]2C[C@H]2\C=C\c3ccc4ccccc4c3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 413.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Limberg MB, Birkle DL, Bazan HE, Kaufman HE, Bazan NG. The effect of a new lipoxygenase inhibitor on the production of arachidonic acid metabolites during experimental herpes simplex keratitis. Current eye Research. 1988 Nov;7(11):1131-1135. DOI: 10.3109/02713688809001884.