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MedKoo Cat#: 462048 | Name: Tefluthrin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tefluthrin is a pyrethroid, a class of synthetic insecticides that mimic the structure and properties of the naturally occurring insecticide pyrethrin which is present in the flowers of Chrysanthemum cinerariifolium.

Chemical Structure

Tefluthrin
Tefluthrin
CAS#79538-32-2

Theoretical Analysis

MedKoo Cat#: 462048

Name: Tefluthrin

CAS#: 79538-32-2

Chemical Formula: C17H14ClF7O2

Exact Mass: 418.0571

Molecular Weight: 418.74

Elemental Analysis: C, 48.76; H, 3.37; Cl, 8.47; F, 31.76; O, 7.64

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Tefluthrin; Forza; PP993; Tefluthrine; HSDB 7135
IUPAC/Chemical Name
2,3,5,6-tetrafluoro-4-methylbenzyl (1S,3S)-3-((E)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropane-1-carboxylate
InChi Key
ZFHGXWPMULPQSE-CXQRGBQISA-N
InChi Code
InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4+/t8-,10-/m1/s1
SMILES Code
CC(C(F)=C1F)=C(F)C(F)=C1COC([C@@]2([H])[C@@](C(C)2C)([H])/C([H])=C(Cl)\C(F)(F)F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 418.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Effects of the β1 Auxiliary Subunit on Modification of Rat Nav1.6 Sodium Channels Expressed in HEK293 Cells by the Pyrethroid Insecticides Tefluthrin and Deltamethrin Bingjun He, David M. Soderlund Toxicol Appl Pharmacol. Author manuscript; available in PMC 2017 Jan 15.Published in final edited form as: Toxicol Appl Pharmacol. 2016 Jan 15; 291: 58–69. Published online 2015 Dec 19. doi: 10.1016/j.taap.2015.12.007 PMCID: PMC4718755 2: Differential State-Dependent Modification of Rat Nav1.6 Sodium Channels Expressed in Human Embryonic Kidney (HEK293) Cells by the Pyrethroid Insecticides Tefluthrin and Deltamethrin Bingjun He, David M. Soderlund Toxicol Appl Pharmacol. Author manuscript; available in PMC 2012 Dec 15.Published in final edited form as: Toxicol Appl Pharmacol. 2011 Dec 15; 257(3): 377–387. Published online 2011 Sep 29. doi: 10.1016/j.taap.2011.09.021 PMCID: PMC3226847 3: Differential state-dependent modification of inactivation-deficient Nav1.6 sodium channels by the pyrethroid insecticides S-bioallethrin, tefluthrin and deltamethrin Samantha J. McCavera, David M. Soderlund Neurotoxicology. Author manuscript; available in PMC 2013 Jun 1.Published in final edited form as: Neurotoxicology. 2012 Jun; 33(3): 384–390. Published online 2012 Mar 28. doi: 10.1016/j.neuro.2012.03.007 PMCID: PMC3574822 4: Human and Rat Nav1.3 Voltage-Gated Sodium Channels Differ in Inactivation Properties and Sensitivity to the Pyrethroid Insecticide Tefluthrin Jianguo Tan, David M. Soderlund Neurotoxicology. Author manuscript; available in PMC 2010 Jan 1.Published in final edited form as: Neurotoxicology. 2009 Jan; 30(1): 81–89. Published online 2008 Nov 5. doi: 10.1016/j.neuro.2008.10.008 PMCID: PMC2696113 5: Divergent Actions of the Pyrethroid Insecticides S-Bioallethrin, Tefluthrin and Deltamethrin on Rat Nav1.6 Sodium Channels Jianguo Tan, David M. Soderlund Toxicol Appl Pharmacol. Author manuscript; available in PMC 2011 Sep 15.Published in final edited form as: Toxicol Appl Pharmacol. 2010 Sep 15; 247(3): 229–237. Published online 2010 Jul 17. doi: 10.1016/j.taap.2010.07.001 PMCID: PMC2929565