IUPAC/Chemical Name
(3S,5S,8S,9S,10R,13S,14S,17R)-17-((2S,3R,4R,5S)-3,4-dihydroxy-5,6-dimethylheptan-2-yl)-3-hydroxy-10,13-dimethylhexadecahydro-6H-cyclopenta[a]phenanthren-6-one
InChi Key
SBSXXCCMIWEPEE-GZKYLSGOSA-N
InChi Code
InChI=1S/C28H48O4/c1-15(2)16(3)25(31)26(32)17(4)20-7-8-21-19-14-24(30)23-13-18(29)9-11-28(23,6)22(19)10-12-27(20,21)5/h15-23,25-26,29,31-32H,7-14H2,1-6H3/t16-,17-,18-,19-,20+,21-,22-,23+,25+,26+,27+,28+/m0/s1
SMILES Code
CC([C@]([C@](O)([H])[C@@](O)([H])[C@@]([C@@]1([H])CC[C@@]2([H])[C@]([C@]3([H])CC[C@]12C)([H])CC([C@@]4([H])C[C@](O)([H])CC[C@]34C)=O)([H])C)([H])C)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
448.69
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: YCZ-18 Is a New Brassinosteroid Biosynthesis Inhibitor Keimei Oh, Tadashi Matsumoto, Ayumi Yamagami, Atushi Ogawa, Kazuhiro Yamada, Ryuichiro Suzuki, Takayuki Sawada, Shozo Fujioka, Yuko Yoshizawa, Takeshi Nakano PLoS One. 2015; 10(3): e0120812. Published online 2015 Mar 20. doi: 10.1371/journal.pone.0120812 PMCID: PMC4368189
2: Fenarimol, a Pyrimidine-Type Fungicide, Inhibits Brassinosteroid Biosynthesis Keimei Oh, Tadashi Matsumoto, Ayumi Yamagami, Tomoki Hoshi, Takeshi Nakano, Yuko Yoshizawa Int J Mol Sci. 2015 Aug; 16(8): 17273–17288. Published online 2015 Jul 29. doi: 10.3390/ijms160817273 PMCID: PMC4581192
3: Blockage of Brassinosteroid Biosynthesis and Sensitivity Causes Dwarfism in Garden Pea. T. Nomura, M. Nakayama, J. B. Reid, Y. Takeuchi, T. Yokota Plant Physiol. 1997 Jan; 113(1): 31–37. doi: 10.1104/pp.113.1.31 PMCID: PMC158112
4: Metagenomics and Faecal Metabolomics Integrative Analysis towards the Impaired Glucose Regulation and Type 2 Diabetes in Uyghur-Related Omics Rebiya Nuli, Jureti Azhati, Junxiu Cai, Aizhatiguli Kadeer, Bing Zhang, Patamu Mohemaiti J Diabetes Res. 2019; 2019: 2893041. Published online 2019 Nov 18. doi: 10.1155/2019/2893041 PMCID: PMC6885810
5: In vitro and in vivo evidence for the inhibition of brassinosteroid synthesis by propiconazole through interference with side chain hydroxylation Keimei Oh, Tadashi Matsumoto, Tomoki Hoshi, Yuko Yoshizawa Plant Signal Behav. 2016 May; 11(5): e1158372. Published online 2016 Mar 17. doi: 10.1080/15592324.2016.1158372 PMCID: PMC4977458
