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MedKoo Cat#: 534621 | Name: IFNalpha-IFNAR-IN-1 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IFNalpha-IFNAR-IN-1 HCl is a nonpeptidic inhibitor of interferon-alpha-IFNalpha-R Interaction, preventing IFN-alpha and IFNAR interaction-dependent IFN-alpha production.

Chemical Structure

IFNalpha-IFNAR-IN-1 HCl
IFNalpha-IFNAR-IN-1 HCl
CAS#2070014-98-9

Theoretical Analysis

MedKoo Cat#: 534621

Name: IFNalpha-IFNAR-IN-1 HCl

CAS#: 2070014-98-9

Chemical Formula: C18H18ClNS

Exact Mass: 315.0848

Molecular Weight: 315.86

Elemental Analysis: C, 68.45; H, 5.74; Cl, 11.22; N, 4.43; S, 10.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
IFNalpha-IFNAR-IN-1 HCl
IUPAC/Chemical Name
N-Methyl-1-(2-(naphthalen-1-ylthio)phenyl)methanamine Hydrochloride
InChi Key
QTESJCPDPNGOLF-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H17NS.ClH/c1-19-13-15-8-3-5-11-17(15)20-18-12-6-9-14-7-2-4-10-16(14)18;/h2-12,19H,13H2,1H3;1H
SMILES Code
CNCC1=CC=CC=C1SC2=C3C=CC=CC3=CC=C2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 315.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Paldus B, Lee MH, Jones HM, McAuley SA, Horsburgh JC, Roem KL, Ward GM, MacIsaac RJ, Cohen N, Colman PG, Jenkins AJ, O'Neal DN. Glucose Control Using a Standard Versus an Enhanced Hybrid Closed Loop System: A Randomized Crossover Study. Diabetes Technol Ther. 2019 Jan;21(1):56-58. doi: 10.1089/dia.2018.0279. PMID: 30620641. 2: Tiacci E, Pettirossi V, Schiavoni G, Falini B. Genomics of Hairy Cell Leukemia. J Clin Oncol. 2017 Mar 20;35(9):1002-1010. doi: 10.1200/JCO.2016.71.1556. Epub 2017 Feb 13. PMID: 28297625; PMCID: PMC5455681. 3: Salem DA, Scott D, McCoy CS, Liewehr DJ, Venzon DJ, Arons E, Kreitman RJ, Stetler-Stevenson M, Yuan CM. Differential Expression of CD43, CD81, and CD200 in Classic Versus Variant Hairy Cell Leukemia. Cytometry B Clin Cytom. 2019 Jul;96(4):275-282. doi: 10.1002/cyto.b.21785. Epub 2019 May 11. PMID: 31077558. 4: Gillespie BR, Patel CA, Rothrock MM, Heard GL, Setser DW, Holmes BE. Experimental and Computational Studies of Unimolecular 1,1-HX (X = F, Cl) Elimination Reactions of C2D5CHFCl: Role of Carbene:HF and HCl Adducts in the Exit Channel of RCHFCl and RCHCl2 Reactions. J Phys Chem A. 2019 Apr 4;123(13):2621-2633. doi: 10.1021/acs.jpca.9b00779. Epub 2019 Mar 20. PMID: 30841697. 5: Faulds ER, Zappe J, Dungan KM. REAL-WORLD IMPLICATIONS OF HYBRID CLOSE LOOP (HCL) INSULIN DELIVERY SYSTEM. Endocr Pract. 2019 May;25(5):477-484. doi: 10.4158/EP-2018-0515. Epub 2019 Mar 13. PMID: 30865545; PMCID: PMC6832708. 6: Maitre E, Bertrand P, Maingonnat C, Viailly PJ, Wiber M, Naguib D, Salaün V, Cornet E, Damaj G, Sola B, Jardin F, Troussard X. New generation sequencing of targeted genes in the classical and the variant form of hairy cell leukemia highlights mutations in epigenetic regulation genes. Oncotarget. 2018 Jun 22;9(48):28866-28876. doi: 10.18632/oncotarget.25601. PMID: 29989027; PMCID: PMC6034755. 7: Janus A, Robak T. Moxetumomab pasudotox for the treatment of hairy cell leukemia. Expert Opin Biol Ther. 2019 Jun;19(6):501-508. doi: 10.1080/14712598.2019.1614558. Epub 2019 May 10. PMID: 31045462. 8: Graf C, Bernkop-Schnürch A, Egyed A, Koller C, Prieschl-Grassauer E, Morokutti-Kurz M. Development of a nasal spray containing xylometazoline hydrochloride and iota-carrageenan for the symptomatic relief of nasal congestion caused by rhinitis and sinusitis. Int J Gen Med. 2018 Jul 4;11:275-283. doi: 10.2147/IJGM.S167123. PMID: 30013382; PMCID: PMC6037157. 9: Song YN, Hong HG, Son JS, Kwon YO, Lee HH, Kim HJ, Park JH, Son MJ, Oh JG, Yoon MH. Investigation of Ginsenosides and Antioxidant Activities in the Roots, Leaves, and Stems of Hydroponic-Cultured Ginseng (Panax ginseng Meyer). Prev Nutr Food Sci. 2019 Sep;24(3):283-292. doi: 10.3746/pnf.2019.24.3.283. Epub 2019 Sep 30. PMID: 31608253; PMCID: PMC6779092. 10: Abiero A, Ryu IS, Botanas CJ, Custodio RJP, Sayson LV, Kim M, Lee HJ, Kim HJ, Seo JW, Cho MC, Lee KW, Yoo SY, Jang CG, Lee YS, Cheong JH. Four Novel Synthetic Tryptamine Analogs Induce Head-Twitch Responses and Increase 5-HTR2a in the Prefrontal Cortex in Mice. Biomol Ther (Seoul). 2019 Jun 24;28(1):83-91. doi: 10.4062/biomolther.2019.049. Epub ahead of print. PMID: 31230432; PMCID: PMC6939696.

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