MedKoo Cat#: 534616 | Name: IPS-02001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

IPS-02001 is a novel inhibitor of protein-protein interaction (PPI), targeting integrin αvβ3-osteopontin interface, blocking OC maturation from murine bone marrow-derived macrophages, as well as the resorptive function of OCs, impairing downstream signaling of integrin αvβ3 linked to Pyk2, c-Src, PLCγ2, and Vav3.

Chemical Structure

IPS-02001
IPS-02001
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 534616

Name: IPS-02001

CAS#: N/A

Chemical Formula: C15H14O7

Exact Mass: 306.0740

Molecular Weight: 306.27

Elemental Analysis: C, 58.83; H, 4.61; O, 36.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
IPS-02001; IPS 02001; IPS02001
IUPAC/Chemical Name
3,5,10-Trihydroxy-7-methoxy-3-methyl-1,4-dihydrobenzo[g]isochromene-6,9-dione
InChi Key
FKJXMYJPOKQPSS-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14O7/c1-15(20)4-6-7(5-22-15)13(18)10-8(16)3-9(21-2)14(19)11(10)12(6)17/h3,17-18,20H,4-5H2,1-2H3
SMILES Code
O=C(C1=C(O)C(CC(C)(O)OC2)=C2C(O)=C13)C(OC)=CC3=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 306.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Park D, Park CW, Choi Y, Lin J, Seo DH, Kim HS, Lee SY, Kang IC. A novel small-molecule PPI inhibitor targeting integrin αvβ3-osteopontin interface blocks bone resorption in vitro and prevents bone loss in mice. Biomaterials. 2016 Aug;98:131-42. doi: 10.1016/j.biomaterials.2016.05.007. Epub 2016 May 5. PMID: 27187277.