Indomethacin salicylate | CAS#65474-39-7 | antiinflammatory drug

MedKoo Cat#: 462036 | Name: Indomethacin salicylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Indomethacin salicylate is an antiinflammatory drug. It has shown remarkable inhibitory effects on carrageenin edema, ultraviolet erythema and adjuvant arthritis.

Chemical Structure

Indomethacin salicylate

CAS#65474-39-7

Theoretical Analysis

MedKoo Cat#: 462036

Name: Indomethacin salicylate

CAS#: 65474-39-7

Chemical Formula: C26H20ClNO6

Exact Mass: 477.0979

Molecular Weight: 477.90

Elemental Analysis: C, 65.35; H, 4.22; Cl, 7.42; N, 2.93; O, 20.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Indomethacin salicylate; TB 219; BRN 0464919

IUPAC/Chemical Name

Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-, ester with salicylic acid

InChi Key

ZMVHVVYABPAONG-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H20ClNO6/c1-15-20(14-24(29)34-23-6-4-3-5-19(23)26(31)32)21-13-18(33-2)11-12-22(21)28(15)25(30)16-7-9-17(27)10-8-16/h3-13H,14H2,1-2H3,(H,31,32)

SMILES Code

O=C(O)C1=CC=CC=C1OC(CC2=C(C)N(C(C3=CC=C(Cl)C=C3)=O)C4=C2C=C(OC)C=C4)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 477.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tanaka I, Yoshizumi H, Tanaka Y, et al. Pharmacological profiles of 2-carboxyphenyl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate and 2-[(2-carboxyphenoxy)-carbonyl]phenyl-1-(4-chlorobenzoyl)-5-meth oxy-2- methylindole-3-acetate, new antiinflammatory agents. Arzneimittelforschung. 1986;36(4):703‐709.