MedKoo Cat#: 534602 | Name: Enoxolone sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Enoxolone sodium is a bioactive chemical.

Chemical Structure

Enoxolone sodium
Enoxolone sodium
CAS#2508-76-1

Theoretical Analysis

MedKoo Cat#: 534602

Name: Enoxolone sodium

CAS#: 2508-76-1

Chemical Formula: C30H45NaO4

Exact Mass: 492.3216

Molecular Weight: 492.68

Elemental Analysis: C, 73.14; H, 9.21; Na, 4.67; O, 12.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Enoxolone sodium
IUPAC/Chemical Name
Olean-12-en-30-oic acid, 3beta-hydroxy-11-oxo-, monosodium salt
InChi Key
MOCOXAJEZKHXSF-IHMBCTQLSA-M
InChi Code
InChI=1S/C30H46O4.Na/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6;/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34);/q;+1/p-1/t19-,21-,22-,23+,26+,27-,28-,29+,30+;/m0./s1
SMILES Code
CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CC[C@@](C)(C[C@]2(C1=C3)[H])C([O-])=O)C)C)4C)5[H])[C@@H](O)CC[C@]5(C)[C@@]4([H])C3=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 492.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: She NN, Hou Y, Wang YH, Gui Y, Xi GH, Chen XW, Chen KB, Ma CX, Liu XH, Zhang XB. [Effects of 18β-sodium glycyrrhetinic acid on TNF-α expression in rats with allergic rhinitis]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Mar;33(3):262-266. Chinese. doi: 10.13201/j.issn.1001-1781.2019.03.019. PMID: 30813699. 2: Yang J, Xi K, Gui Y, Wang Y, Zhang F, Ma C, Hong H, Liu X, Meng N, Zhang X. [The effect of 18β-sodium glycyrrhetinic acid on the nasal mucosa epithelial cilia in rat models of allergic rhinitis]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Dec;29(23):2060-4. Chinese. PMID: 27101679. 3: Morris DJ, Ridlon JM. Glucocorticoids and gut bacteria: "The GALF Hypothesis" in the metagenomic era. Steroids. 2017 Sep;125:1-13. doi: 10.1016/j.steroids.2017.06.002. Epub 2017 Jun 15. PMID: 28624548. 4: Ji J, Gui Y, Wang YH, Hou Y, Chen KB, Xi KH, Chen XW, Liu XH, Zhang XB. [The inhibition of 18β-sodium glycyrrhetinic acid on thymic stromal lymphopoietin expression in the nasal mucosa of allergic rhinitis rats]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jun 7;54(6):456-463. Chinese. doi: 10.3760/cma.j.issn.1673-0860.2019.06.011. PMID: 31262112. 5: Jeon YD, Kang SH, Bang KS, Chang YN, Lee JH, Jin JS. Glycyrrhetic Acid Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Vivo. Molecules. 2016 Apr 22;21(4):523. doi: 10.3390/molecules21040523. PMID: 27110761; PMCID: PMC6273862. 6: Ran X, Xiang J, Song PP, Jiang L, Liu BK, Hu Y. Effects of gap junctions blockers on fast ripples and connexin in rat hippocampi after status epilepticus. Epilepsy Res. 2018 Oct;146:28-35. doi: 10.1016/j.eplepsyres.2018.07.010. Epub 2018 Jul 20. PMID: 30056318. 7: Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate. Int J Toxicol. 2007;26 Suppl 2:79-112. doi: 10.1080/10915810701351228. PMID: 17613133. 8: Zhu G, Ma S, Li X, Zhang P, Tang L, Cao L, Liu A, Sugita T, Tomoda T. The effect of ethanol extract of Glycyrrhiza uralensis on the voltage-gated sodium channel subtype 1.4. J Pharmacol Sci. 2018 Feb;136(2):57-65. doi: 10.1016/j.jphs.2017.11.008. Epub 2017 Dec 1. PMID: 29433959. 9: Du Y, Zhang S, Wu H, Zou A, Lei M, Cheng L, Liao Y. Glycyrretinic acid blocks cardiac sodium channels expressed in Xenopus oocytes. J Ethnopharmacol. 2009 Sep 7;125(2):318-23. doi: 10.1016/j.jep.2009.06.016. Epub 2009 Jun 25. PMID: 19559778. 10: Frey FJ, Ferrari P. Pastis and hypertension--what is the molecular basis? Nephrol Dial Transplant. 2000 Oct;15(10):1512-4. doi: 10.1093/ndt/15.10.1512. PMID: 11007814.