Wallichinine is a PAF antagonist that is isolated and purified from the stem of Piper wallichii. Wallichinine can significantly potentiate the effects of two ABCB1, substrates vincristine and doxorubicin, on inhibition of growth, arrest of cell cycle and induction of apoptosis in ABCB1 overexpressing cancer cells, and the overexpression of ABCB1 in cancer cells.
MedKoo Cat#: 462032
Name: Wallichinine
CAS#: 125292-97-9
Chemical Formula: C22H26O5
Exact Mass: 370.1780
Molecular Weight: 370.45
Elemental Analysis: C, 71.33; H, 7.07; O, 21.59
The following data is based on the product molecular weight 370.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
