Tacrolimus anhydrous 8-epimer | CAS#129212-35-7 | immunosuppressive drug

MedKoo Cat#: 462012 | Name: Tacrolimus anhydrous 8-epimer

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tacrolimus anhydrous 8-epimer is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.

Chemical Structure

Tacrolimus anhydrous 8-epimer

CAS#129212-35-7

Theoretical Analysis

MedKoo Cat#: 462012

Name: Tacrolimus anhydrous 8-epimer

CAS#: 129212-35-7

Chemical Formula: C44H69NO12

Exact Mass: 803.4820

Molecular Weight: 804.03

Elemental Analysis: C, 65.73; H, 8.65; N, 1.74; O, 23.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Tacrolimus anhydrous 8-epimer; 8-Epitacrolimus; Tacrolimus monohydrate impurity D; 8-epi-Tacrolimus

IUPAC/Chemical Name

A name could not be generated for this structure.

InChi Key

QJJXYPPXXYFBGM-NCGCDJFJSA-N

InChi Code

InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19+,27-21+/t26-,28+,29+,30-,31-,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1

SMILES Code

CO[C@@H]1C[C@H](/C=C([C@H]2OC([C@@H]3CCCCN3C(C([C@@]4(O[C@@H]([C@@H](OC)C[C@H]4C)[C@@H](OC)C[C@H](C/C(C)=C/[C@@H](C(C[C@@H]([C@H]2C)O)=O)CC=C)C)O)=O)=O)=O)\C)CC[C@H]1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 804.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.