MedKoo Cat#: 461984 | Name: DL 175
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DL 175 is a potent, selective, and structurally novel GPR84 agonist and the first to display significantly biased signaling across GPR84-overexpressing cells, primary murine macrophages, and human U937 cells.

Chemical Structure

DL 175
DL 175
CAS#2487253-25-6

Theoretical Analysis

MedKoo Cat#: 461984

Name: DL 175

CAS#: 2487253-25-6

Chemical Formula: C17H14ClNO2

Exact Mass: 299.0713

Molecular Weight: 299.75

Elemental Analysis: C, 68.12; H, 4.71; Cl, 11.83; N, 4.67; O, 10.67

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
50mg USD 1,250.00 2 Weeks
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Related CAS #
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Synonym
DL 175; DL175; DL-175;
IUPAC/Chemical Name
3-(2-((4-Chloronaphthalen-1-yl)oxy)ethyl)pyridine 1-oxide
InChi Key
FXOVKEUUTXBOJZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H14ClNO2/c18-16-7-8-17(15-6-2-1-5-14(15)16)21-11-9-13-4-3-10-19(20)12-13/h1-8,10,12H,9,11H2
SMILES Code
ClC1=C2C=CC=CC2=C(OCCC3=C[N+]([O-])=CC=C3)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 299.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lucy D, Purvis GSD, Zeboudj L, Chatzopoulou M, Recio C, Bataille CJR, Wynne GM, Greaves DR, Russell AJ. A Biased Agonist at Immunometabolic Receptor GPR84 Causes Distinct Functional Effects in Macrophages. ACS Chem Biol. 2019 Sep 20;14(9):2055-2064. doi: 10.1021/acschembio.9b00533. Epub 2019 Sep 10. PubMed PMID: 31465201.