MedKoo Cat#: 461966 | Name: Sdz 210-096

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sdz 210-096 is a novel opiate antagonist. It is a novel 14 beta-benzyl morphinan derivative with antagonistic actions at mu and kappa opiate receptors. This compound has been characterized for luteinizing hormone (LH) secretion-stimulating effects in a variety of experimental paradigms in the rat.

Chemical Structure

Sdz 210-096
Sdz 210-096
CAS#109026-86-0

Theoretical Analysis

MedKoo Cat#: 461966

Name: Sdz 210-096

CAS#: 109026-86-0

Chemical Formula: C27H31NO2

Exact Mass: 401.2355

Molecular Weight: 401.55

Elemental Analysis: C, 80.76; H, 7.78; N, 3.49; O, 7.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sdz 210-096; Sdz210096
IUPAC/Chemical Name
Morphinan-6-one, 17-(cyclopropylmethyl)-3-hydroxy-14-(phenylmethyl)-
InChi Key
NLUNUQJHWWKYNI-ZONZVBGPSA-N
InChi Code
InChI=1S/C27H31NO2/c29-22-9-8-21-14-25-27(16-19-4-2-1-3-5-19)11-10-23(30)17-26(27,24(21)15-22)12-13-28(25)18-20-6-7-20/h1-5,8-9,15,20,25,29H,6-7,10-14,16-18H2/t25-,26-,27-/m1/s1
SMILES Code
O=C1C[C@]23C4=CC(O)=CC=C4C[C@@H](N(CC5CC5)CC3)[C@]2(CC6=CC=CC=C6)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Landymore KM, Giles A, Wilkinson M. Ex vivo determination of opiate antagonist binding at mu-opioid ([3H]-DAGO) receptors in hypothalamic micropunches from maturing female rats: comparison between SDZ 210-096 and nalmefene.Neuropeptides. 1992 Mar;21(3):175-82. PubMed PMID: 1321363. 2: Siegel RA, Révész L. Effects of the novel opiate antagonist, SDZ 210-096, on luteinizing hormone secretion in the rat. J Pharmacol Exp Ther. 1989 Apr;249(1):264-70. PubMed PMID: 2540315.