MedKoo Cat#: 461963 | Name: Sulphamoprine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulphamoprine is a class of sulfonamides which is highly active against dihydropteroate synthase form Toxoplasma gondii, Pneumocystis carinii, and Mycobacterium avium. Sulphamoprine, when given in the diet at levels from 0.025% upwards to pregnant rats and mice, produced abnormalities of eruption of the incisor teeth and of the skull of the offspring. Rabbits are not susceptible to this teratogenic action.

Chemical Structure

Sulphamoprine
Sulphamoprine
CAS#155-91-9

Theoretical Analysis

MedKoo Cat#: 461963

Name: Sulphamoprine

CAS#: 155-91-9

Chemical Formula: C12H144N4OS

Exact Mass: 310.0736

Molecular Weight: 310.33

Elemental Analysis: C, 46.45; H, 4.55; N, 18.05; O, 20.62; S, 10.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sulphamoprine; ICI 3435; ICI3435; ICI-3435; NSC 8560; NSC-8560; NSC8560;
IUPAC/Chemical Name
Benzenesulfonamide, 4-amino-N-(4,6-dimethoxy-2-pyrimidinyl)-
InChi Key
RMSFTZDTJHYIFE-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H14N4O4S/c1-19-10-7-11(20-2)15-12(14-10)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
SMILES Code
O=S(C1=CC=C(N)C=C1)(NC2=NC(OC)=CC(OC)=N2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 310.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: PAGET GE, THORPE E. A TERATOGENIC EFFECT OF A SULPHONAMIDE IN EXPERIMENTAL ANIMALS. Br J Pharmacol Chemother. 1964 Oct;23:305-12. PubMed PMID: 14228132; PubMed Central PMCID: PMC1704094.