MedKoo Cat#: 461950 | Name: Scropolioside D

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Scropolioside D is an iridoid glycoside from aerial parts of Scrophularia ilwensis. It has been found to possess significant antidiabetic and antiinflammatory activity.

Chemical Structure

Scropolioside D
Scropolioside D
CAS#148000-43-5

Theoretical Analysis

MedKoo Cat#: 461950

Name: Scropolioside D

CAS#: 148000-43-5

Chemical Formula: C34H42O17

Exact Mass: 722.2422

Molecular Weight: 722.69

Elemental Analysis: C, 56.51; H, 5.86; O, 37.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Scropolioside D; 6-O-((2'',4''-Di-O-acetyl-3''-O-trans-cinnamoyl)-alpha-L-rhamnopyranosyl)catalpol
IUPAC/Chemical Name
beta-D-Glucopyranoside, 6-((2,4-di-O-acetyl-6-deoxy-3-O-(1-oxo-3-phenyl-2-propenyl)-alpha-L-mannopyranosyl)oxy)-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta(E),6aalpha))-
InChi Key
XTDOKCBBQODVJW-LTDPXCIYSA-N
InChi Code
InChI=1S/C34H42O17/c1-15-26(45-16(2)37)28(48-21(39)10-9-18-7-5-4-6-8-18)29(46-17(3)38)33(44-15)49-27-19-11-12-43-31(22(19)34(14-36)30(27)51-34)50-32-25(42)24(41)23(40)20(13-35)47-32/h4-12,15,19-20,22-33,35-36,40-42H,13-14H2,1-3H3/b10-9+/t15-,19+,20+,22+,23+,24-,25+,26-,27-,28+,29+,30-,31-,32-,33-,34+/m0/s1
SMILES Code
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1O[C@H]2[C@@]3([H])[C@@]([C@H](O[C@H]4[C@@H]([C@@H]([C@H]([C@H](C)O4)OC(C)=O)OC(/C=C/C5=CC=CC=C5)=O)OC(C)=O)[C@@]6([H])[C@]3(CO)O6)([H])C=CO2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 722.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang L, Zhu T, Qian F, Xu J, Dorje G, Zhao Z, Guo F, Li Y. Iridoid glycosides isolated from Scrophularia dentata Royle ex Benth. and their anti-inflammatory activity. Fitoterapia. 2014 Oct;98:84-90. doi: 10.1016/j.fitote.2014.07.005. Epub 2014 Jul 10. PubMed PMID: 25016952. 2: Ahmed B, Al-Rehaily AJ, Al-Howiriny TA, El-Sayed KA, Ahmad MS. Scropolioside-D2 and harpagoside-B: two new iridoid glycosides from Scrophularia deserti and their antidiabetic and antiinflammatory activity. Biol Pharm Bull. 2003 Apr;26(4):462-7. PubMed PMID: 12673026. 3: Caliş I, Zor M, Başaran AA, Wright AD, Sticher O. Karsoside and scropolioside D, two new iridoid glycosides from Scrophularia ilwensis. J Nat Prod. 1993 Apr;56(4):606-9. PubMed PMID: 8496707.