PVHD303 | CAS#unknown | anticancer agent

MedKoo Cat#: 593199 | Name: PVHD303

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PVHD303 is a potent anticancer agent. It inhibits the growth of tumors dose-dependently in the HCT116 human colon cancer xenograft model in vivo.

Chemical Structure

PVHD303

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 593199

Name: PVHD303

CAS#: unknown

Chemical Formula: C21H18N2O3

Exact Mass: 346.1317

Molecular Weight: 346.39

Elemental Analysis: C, 72.82; H, 5.24; N, 8.09; O, 13.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PVHD303; PVHD-303; PVHD-303

IUPAC/Chemical Name

1-(2-(furan-3-yl)quinazolin-4-yl)-1-(4-methoxyphenyl)ethan-1-ol

InChi Key

USLHJGWCQIJIGV-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H18N2O3/c1-21(24,15-7-9-16(25-2)10-8-15)19-17-5-3-4-6-18(17)22-20(23-19)14-11-12-26-13-14/h3-13,24H,1-2H3

SMILES Code

CC(C1=CC=C(OC)C=C1)(C2=C3C=CC=CC3=NC(C4=COC=C4)=N2)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 346.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yumiko Suzuki, Ayana Otake, Satoshi Ueno, Kensuke Hayashi, Hirosuke Ishii, Nao Miyoshi, Kenta Kuroiwa, Masashi Tachikawa,Yuki Fujimak, Kotaro Nishiyama, Kei Manabe, Ryuta Yamazaki, Akira Asai. Discovery of a Potent Anticancer Agent PVHD303 with in Vivo Activity. J Med Chem. 2020 May 8. https://doi.org/10.1021/acsmedchemlett.0c00119.