LML134 is an orally active and high selective Histamine 3 receptor (H3R) inverse agonist with Kis of 0.3 nM and 12 nM for hH3R cAMP and hH3R bdg. LML134 is potentially useful for the Clinical Treatment of Excessive Sleep Disorders.
MedKoo Cat#: 555764
Name: LML-134
CAS#: 1542135-76-1
Chemical Formula: C19H29N5O3
Exact Mass: 375.2270
Molecular Weight: 375.47
Elemental Analysis: C, 60.78; H, 7.79; N, 18.65; O, 12.78
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 12.5 | 33.29 |
The following data is based on the product molecular weight 375.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
