MedKoo Cat#: 555761 | Name: AKOS B018304
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AKOS B018304 is a potent inhibitor of chikungunya virus with low micro molar activity.

Chemical Structure

AKOS B018304
AKOS B018304
CAS#6308-22-1

Theoretical Analysis

MedKoo Cat#: 555761

Name: AKOS B018304

CAS#: 6308-22-1

Chemical Formula: C10H6N2O3S2

Exact Mass: 265.9820

Molecular Weight: 266.29

Elemental Analysis: C, 45.11; H, 2.27; N, 10.52; O, 18.02; S, 24.08

Price and Availability

Size Price Availability Quantity
50mg USD 850.00 2 Weeks
100mg USD 1,450.00 2 Weeks
200mg USD 2,450.00 2 Weeks
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Synonym
AKOS B018304; AKOS-B018304; AKOSB018304; AKOS B018304; AKOS B 018304; AKOSB 018304; AKOSB-018304;
IUPAC/Chemical Name
(5Z)-5-(2-Nitrobenzylidene)-2-sulfanyl-1,3-thiazol-4(5H)-one
InChi Key
CTTRUEBEEFZQBL-YVMONPNESA-N
InChi Code
InChI=1S/C10H6N2O3S2/c13-9-8(17-10(16)11-9)5-6-3-1-2-4-7(6)12(14)15/h1-5H,(H,11,13,16)/b8-5-
SMILES Code
O=C1N=C(S)S/C1=C\C2=CC=CC=C2[N+]([O-])=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 266.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Jadav SS, Sinha BN, Hilgenfeld R, Pastorino B, de Lamballerie X, Jayaprakash V. Thiazolidone derivatives as inhibitors of chikungunya virus. Eur J Med Chem. 2015 Jan 7;89:172-8. doi: 10.1016/j.ejmech.2014.10.042. Epub 2014 Oct 16. PMID: 25462237.