SLCB050 is a novel compound that blocks the interaction between DX2 and p14/ARF in vitro and in vivo SLCB050 reduced the viability of human lung cancer cells, especially small cell lung cancer cells, in a p14/ARF-dependent manner. DX2 promotes lung cancer progression and its activity may be thwarted as a strategy to treat patients with lung cancers exhibiting elevated DX2 levels using SLCB050.
MedKoo Cat#: 593177
Name: SLCB050
CAS#: 1848971-16-3
Chemical Formula: C21H18O6
Exact Mass: 366.1103
Molecular Weight: 366.37
Elemental Analysis: C, 68.85; H, 4.95; O, 26.20
The following data is based on the product molecular weight 366.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
