RPN77612 is a synthetic curcuminoid molecule with multiple bio-actvities, including (1) cytotoxic effect on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines; (2) ameliorating amyloid precursor protein (APP) and tau protein pathology and rescues cognitive deficits in neurodegenerative diseases; (3) inhibitor of transcription factor NF-κB and activators of Nrf2 and uses thereof for treatment of neurological disoders and inflammatory diseases. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 408074
Name: RPN77612
CAS#: 39777-61-2
Chemical Formula: C19H18O3
Exact Mass: 294.1256
Molecular Weight: 294.35
Elemental Analysis: C, 77.53; H, 6.16; O, 16.31
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Soluble in DMSO | 0.0 | 0.00 |
The following data is based on the product molecular weight 294.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
