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MedKoo Cat#: 533817 | Name: MOA-stilbene

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MOA-stilbene, also known as 3-Methoxy-2-(2-styrylphenyl)propenic acid methyl ester, is a fluorescence inhibitor. MOA-stilbene is a new tool for investigation of the reactions of the chloroplast cytochrome bf complex. MOA-stilbene is known to be a specific inhibitor of the Qo site of mammalian cytochrome bc 1 complex.

Chemical Structure

MOA-stilbene
CAS#103455-29-4

Theoretical Analysis

MedKoo Cat#: 533817

Name: MOA-stilbene

CAS#: 103455-29-4

Chemical Formula: C19H18O3

Exact Mass: 294.1256

Molecular Weight: 294.35

Elemental Analysis: C, 77.53; H, 6.16; O, 16.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
beta-Methoxyacrylate stilbene; beta-Moa-stilbene; Moa stilbene;
IUPAC/Chemical Name
3-Methoxy-2-(2-styrylphenyl)propenic acid methyl ester
InChi Key
VEJCBCPEURAYAS-MEAXDALNSA-N
InChi Code
InChI=1S/C19H18O3/c1-21-14-18(19(20)22-2)17-11-7-6-10-16(17)13-12-15-8-4-3-5-9-15/h3-14H,1-2H3/b13-12+,18-14+
SMILES Code
O=C(OC)/C(C1=CC=CC=C1/C=C/C2=CC=CC=C2)=C/OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Brandt U, Djafarzadeh-Andabili R. Binding of MOA-stilbene to the mitochondrial cytochrome bc1 complex is affected by the protonation state of a redox-Bohr group of the 'Rieske' iron-sulfur protein. Biochim Biophys Acta. 1997 Oct 20;1321(3):238-42. doi: 10.1016/s0005-2728(97)00060-1. PMID: 9393641. 2: Rich PR, Madgwick SA, Wiggins TE. Effects of analogues of MOA-stilbene on the chloroplast cytochrome bf complex. Biochem Soc Trans. 1994 Feb;22(1):217-21. doi: 10.1042/bst0220217. PMID: 8206233. 3: Klughammer C, Schreiber U. Selective interaction of valinomycin/K+ with the cytochrome bf complex of chloroplasts. Synergistic effect with MOA stilbene on extent of cytochrome b563 reduction in continuous light. FEBS Lett. 1993 Dec 28;336(3):491-5. doi: 10.1016/0014-5793(93)80862-o. PMID: 8282117. 4: Rich PR, Madgwick SA, Brown S, von Jagow G, Brandt U. MOA-stilbene: A new tool for investigation of the reactions of the chloroplast cytochrome bf complex. Photosynth Res. 1992 Dec;34(3):465-77. doi: 10.1007/BF00029819. PMID: 24408840. 5: Rich PR, Madgwick SA, Brown S, Von Jagow G, Brandt U. MOA-stilbene: a new effector of the Qi site of the chloroplast cytochrome bf complex. Biochem Soc Trans. 1991 Aug;19(3):263S. doi: 10.1042/bst019263s. PMID: 1783111.