MedKoo Cat#: 533784 | Name: VTX-27
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

VTX-27 is a novel potent and selective PKCθ inhibitor.

Chemical Structure

VTX-27
VTX-27
CAS#1321924-70-2

Theoretical Analysis

MedKoo Cat#: 533784

Name: VTX-27

CAS#: 1321924-70-2

Chemical Formula: C20H24ClFN6O

Exact Mass: 418.1684

Molecular Weight: 418.90

Elemental Analysis: C, 57.35; H, 5.78; Cl, 8.46; F, 4.54; N, 20.06; O, 3.82

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 3 Weeks
25mg USD 750.00 3 Weeks
50mg USD 1,350.00 3 Weeks
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Related CAS #
No Data
Synonym
VTX-27; VTX 27; VTX27
IUPAC/Chemical Name
(2R)-2-[(2S)-4-[3-Chloro-5-fluoro-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol
InChi Key
HXWARSZQGAFXJM-MGPUTAFESA-N
InChi Code
InChI=1S/C20H24ClFN6O/c1-11(2)20(3,29)15-10-28(8-7-23-15)19-13(21)9-14(22)17(25-19)16-12-5-4-6-24-18(12)27-26-16/h4-6,9,11,15,23,29H,7-8,10H2,1-3H3,(H,24,26,27)/t15-,20+/m0/s1
SMILES Code
C[C@](O)([C@H]1NCCN(C2=NC(C3=C(C=CC=N4)C4=NN3)=C(F)C=C2Cl)C1)C(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 418.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL