ZIKV-IN-K22 is a small-molecule inhibitor targeting the host-cell endoplasmic reticulum (ER) membrane remodeling required for Zika virus (ZIKV) replication. It disrupts virus-induced ER rearrangements, blocking viral genome replication and protein synthesis. ZIKV-IN-K22 has shown broad-spectrum antiviral activity against other flaviviruses, making it a potential lead compound for antiviral drug development.
MedKoo Cat#: 533751
Name: ZIKV-IN-K22
CAS#: 2141978-86-9
Chemical Formula: C27H25BrN2O3
Exact Mass: 504.1049
Molecular Weight: 505.41
Elemental Analysis: C, 64.16; H, 4.99; Br, 15.81; N, 5.54; O, 9.50
The following data is based on the product molecular weight 505.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
