Guggulsterone-52 is a novel inhibitor of the activation of nuclear factor (NF)-κB signaling in bone marrow-derived dendritic cells, significantly inhibiting LPS-induced IL-12p40 and TNF-α gene expression, IκBα degradation, and NF-κB DNA binding activity in BMDCs, attenuating colitis in IL-10 knockout mice.
MedKoo Cat#: 533730
Name: Guggulsterone-52
CAS#: N/A
Chemical Formula: C23H32O2
Exact Mass: 340.2402
Molecular Weight: 340.51
Elemental Analysis: C, 81.13; H, 9.47; O, 9.40
The following data is based on the product molecular weight 340.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
