RO2443 is a dual inhibitor of the MDM2-p53 or MDMX-p53 protein-protein interaction, inducung MDM2 and MDMX dimerization and activating the p53 pathway.
MedKoo Cat#: 533710
Name: RO2443
CAS#: 1416663-79-0
Chemical Formula: C20H14ClF2N3O2
Exact Mass: 401.0743
Molecular Weight: 401.80
Elemental Analysis: C, 59.79; H, 3.51; Cl, 8.82; F, 9.46; N, 10.46; O, 7.96
The following data is based on the product molecular weight 401.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
