TDP222669 is a novel inhibitor of the p53-Hdm2 protein-protein interaction, dose-dependently stabilized P53 and increased P21 and MDM2 expression in JAR choriocarcinoma cells, inducing the p53 regulated gene (PIG-3) and caspase activity.
MedKoo Cat#: 533707
Name: TDP222669
CAS#: N/A
Chemical Formula: C23H15Cl2IN2O4
Exact Mass: 579.9454
Molecular Weight: 581.19
Elemental Analysis: C, 47.53; H, 2.60; Cl, 12.20; I, 21.84; N, 4.82; O, 11.01
The following data is based on the product molecular weight 581.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
