P13I is a novel PROTAC BTK degrader, efficiently degrading ibrutinib-sensitive BTK-WT (wild type), significantly inducing the degradation of ibrutinib-resistant BTK-C481S.
MedKoo Cat#: 533618
Name: P13I
CAS#: 2360561-66-4
Chemical Formula: C46H48N12O9
Exact Mass: 912.3667
Molecular Weight: 912.97
Elemental Analysis: C, 60.52; H, 5.30; N, 18.41; O, 15.77
The following data is based on the product molecular weight 912.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
