ARN14988 is a potent inhibitor of acid ceramidase that increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells.
MedKoo Cat#: 574292
Name: ARN14988
CAS#: 1502027-70-4
Chemical Formula: C16H24ClN3O5
Exact Mass: 373.1404
Molecular Weight: 373.83
Elemental Analysis: C, 51.41; H, 6.47; Cl, 9.48; N, 11.24; O, 21.40
The following data is based on the product molecular weight 373.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
