MedKoo Cat#: 574280 | Name: Hydroxystilbamidine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydroxystilbamidine is a fluorescent neuronal retrograde tracer that labels the neuronal cell body as well as proximal dendrites. It is also a nucleic acid dye that can be used to label DNA and RNA in fixed or unfixed dead cells. It displays an excitation maximum of 360 nm and emission maxima of 450 and 600 nm when bound to DNA but only emits at 450 nm when bound to RNA.

Chemical Structure

Hydroxystilbamidine
Hydroxystilbamidine
CAS#223769-64-0

Theoretical Analysis

MedKoo Cat#: 574280

Name: Hydroxystilbamidine

CAS#: 223769-64-0

Chemical Formula: C18H24N4O7S2

Exact Mass: 472.1086

Molecular Weight: 472.53

Elemental Analysis: C, 45.75; H, 5.12; N, 11.86; O, 23.70; S, 13.57

Price and Availability

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10mg USD 450.00
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Related CAS #
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Synonym
Hydroxystilbamidine
IUPAC/Chemical Name
4-[2-[4-(aminoiminomethyl)phenyl]ethenyl]-3-hydroxy-benzenecarboximidamide, dimethanesulfonate
InChi Key
YGNSQKCULHSJDC-HFPMQDOPSA-N
InChi Code
InChI=1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;
SMILES Code
OC1=C(/C=C/C2=CC=C(C(N)=N)C=C2)C=CC(C(N)=N)=C1.O=S(C)(O)=O.O=S(C)(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Hydroxystilbamidine displays excitation/emission maxima of 323/620 nm, respectively.

Preparing Stock Solutions

The following data is based on the product molecular weight 472.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Akhavan, M., Hoang, T.X., and Havton, L.A. Improved detection of fluorogold-labeled neurons in long-term studies. J. Neurosci. Methods 152(1-2), 156-162 (2006). 2. Li, C., Marshall, C.T., Lu, C., et al. The dynamic distribution of fluoro-gold and its interrelation with neural nitric oxide synthase following intracerebroventricular injection into rat brain. Biotech. Histochem. 81(1), 41-50 (2006). 3. Festy, B., and Daune, M. Hydroxystilbamidine. A nonintercalating drug as a probe of nucleic acid conformation. Biochemistry 12(24), 4827-4834 (1973).