ABQ11 is a novel potent inhinitor of tyrosine kinases, demonstrating antiproliferative effecrs against chronic myelogenous leukemia (CML) K562 cell line with IC50 values of 0.28 ± 0.03 μM, showing approximately three times higher selectivity than imatinib on CML.
MedKoo Cat#: 533506
Name: ABQ11
CAS#: N/A
Chemical Formula: C16H16ClNO4
Exact Mass: 321.0768
Molecular Weight: 321.76
Elemental Analysis: C, 59.73; H, 5.01; Cl, 11.02; N, 4.35; O, 19.89
The following data is based on the product molecular weight 321.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
