Z36 is a novel Bcl-xL inhibitor, upregulating the expression levels of FAM134B, LC3, and Atg9, inducing autophagy along with autophagic cell death, resulting in ER stress and the unfolded protein response (UPR). Note: This product is a mixture of E and Z- isomers.
MedKoo Cat#: 533468
Name: Z36
CAS#: 1243148-19-7
Chemical Formula: C23H24FN3O2
Exact Mass: 393.1853
Molecular Weight: 393.46
Elemental Analysis: C, 70.21; H, 6.15; F, 4.83; N, 10.68; O, 8.13
The following data is based on the product molecular weight 393.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
